Medications to Avoid During Pregnancy

When you're pregnant, medications to avoid during pregnancy, drugs that can cross the placenta and interfere with fetal development. Also known as teratogenic agents, these substances can cause birth defects, developmental delays, or even miscarriage. Not every drug is off-limits, but many common ones — from pain relievers to antidepressants — carry hidden risks you might not expect.

One major concern is NSAIDs, nonsteroidal anti-inflammatory drugs like ibuprofen and naproxen. While fine for short-term use before pregnancy, taking them after 20 weeks can reduce amniotic fluid and affect fetal kidney development. Stimulants, used for ADHD like Adderall or Ritalin, may raise blood pressure and heart rate in both mom and baby, increasing the chance of preterm birth or low birth weight. Then there’s codeine and tramadol, opioid painkillers that can cause neonatal withdrawal syndrome — a condition where newborns experience tremors, feeding problems, and breathing issues after birth.

It’s not just about avoiding the obvious dangers. Some drugs you think are safe aren’t. For example, aspirin in high doses can increase bleeding risk during delivery, while certain acne medications like isotretinoin are known to cause severe birth defects even in small amounts. Even herbal supplements and over-the-counter remedies like black cohosh or high-dose vitamin A can be risky. The key isn’t to panic — it’s to know what’s safe and what’s not. Many conditions like asthma, depression, or high blood pressure need ongoing treatment during pregnancy, but the right drug at the right dose can make all the difference.

You’ll find real-world guidance in the posts below — from how to spot dangerous drug combos to what alternatives doctors actually recommend. Whether you’re managing chronic pain, mental health, or infections, these articles give you the facts without the jargon. No guesswork. No fluff. Just clear, actionable info to help you protect your health and your baby’s.