Malaria Prophylaxis: What You Need to Know Before You Go

Planning a trip to a country where malaria is still a threat? You don’t have to gamble with your health. A solid prophylaxis plan—right drug, timing, and bite protection—keeps you safe and lets you enjoy the adventure.

Choosing the Right Antimalarial

First off, pick a drug that matches the local parasite type and your health profile. Common options include atovaquone‑proguanil (Malarone), doxycycline, and mefloquine. Malarone works quickly and has fewer side effects, but you need to start it a day before you arrive and keep taking it a day after you leave. Doxycycline is cheap and effective against many strains, yet it can cause sun‑sensitivity, so bring sunscreen. Mefloquine is a once‑a‑week pill, great for long trips, but it can trigger vivid dreams or mood changes in some people.

Talk to a travel clinic at least a month ahead. They’ll ask about allergies, existing meds, and liver health—crucial details because some antimalarials interact with other drugs. Once you have the prescription, keep a small backup pack in your carry‑on; you never know when a bag might get delayed.

Practical Tips to Avoid Mosquito Bites

Even the best drug can’t cover a missed dose, so bite protection is your safety net. Wear long sleeves and pants, especially at dusk and dawn when Anopheles mosquitoes bite most. If the fabric feels too hot, choose lightweight, tightly‑woven material that still blocks the insects.

Apply DEET‑based repellents on exposed skin. A 30% concentration offers long‑lasting protection without the heavy smell of higher formulas. For kids, stick to lower concentrations (10‑15%) and reapply more often. Treat clothing and gear with permethrin—just spray it on before you leave; it stays active through several washes.

Sleep under an insecticide‑treated net whenever you’re in a room that isn’t air‑conditioned. Nets are inexpensive, foldable, and work like a shield. If you’re staying in a hotel with screened windows, still bring a portable net for extra peace of mind.

Don’t forget small habits: avoid standing water near your lodging, keep doors and windows closed, and use fans or air‑conditioners when possible. Mosquitoes dislike airflow, so a simple ceiling fan can cut bites dramatically.

Finally, keep a medication diary. Write down the date and time you take each dose, especially if you’re crossing time zones. A quick note on your phone or a small paper card helps you stay on track and prevents missed doses.

With the right drug, diligent timing, and solid bite protection, malaria prophylaxis becomes a routine, not a worry. Stay informed, stick to the plan, and focus on the unforgettable experiences your trip will bring.

By Elizabeth Cox 24 September 2025

Lariam (Mefloquine) vs Other Antimalarials: A Practical Comparison

A detailed, side‑by‑side look at Lariam (mefloquine) and its main alternatives, covering efficacy, dosing, side‑effects and how to choose the best malaria prophylaxis.